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It works by fighting the immune system chemicals that destroy myelin. Additional Information (Medline Plus). Betaseron is a disease-modifying drug prescribed to treat MS. It works by fighting the immune system chemicals that destroy myelin. Additional Information (Medline Plus). Copaxone is a disease-modifying drug prescribed to treat MS. It works by making the harmful immune system cells helpful. Additional Information (Medline Plus). Novantrone is a disease-modifying drug prescribed to treat MS. It works by suppressing the immune system itself, keeping it from attacking both harmful invaders and innocent myelin. Additional Information (Medline Plus). Rebif is a disease-modifying drug prescribed to treat MS. It works by fighting the immune system chemicals that destroy myelin. 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